Tricarboxylic acids and derivatives
Medchemexpress LLC Magnesium citrate 100mg
Magnesium citrate (Trimagnesium dicitrate) is an orally active magnesium-containing compound that can cross the blood-brain barrier (BBB) Magnesium citrate can be used as an intestinal cleanser and is studied for its application in laxatives Magnesium citrate can also increase the pain threshold and is studied for pain-relief purposes[1][2]
Strem, An Ascensus Company CAS# 51805-45-9. 1g. Tris(2-carboxyethyl)phosphine, hydrochloride, 99% TCEP. MFCD00145469
CAS# 51805-45-9. 1g. Tris(2-carboxyethyl)phosphine, hydrochloride, 99% TCEP. MFCD00145469. Molecular Weight: 286.65. Molecular Formula: (HOOCCH2CH2)3PH+Clae. Color/form: white xtl. Strem# 15-7400. http://www.strem.com/catalog/v/15-7400/
Sigma Aldrich Fine Chemicals Biosciences Citrate Synthase Assay Kit
The Citrate Synthase Assay Kit contains all the required reagents (including a positive control enzyme) for a fast and simple measurement of citrate synthase activity in a whole cell extract or in isolated mitochondria. In addition the kit enables testing of the intactness of the mitochondrial inner membrane.
Medchemexpress LLC ζ-Stat trisodium (NSC37044 trisodium) | 31894-34-5 | 97.0% | 450.31 | C10H5Na3O10S3 | 50MG
ζ-Stat trisodium is a small-molecule inhibitor of protein kinase C zeta (PKC-ζ) used in biochemical and cellular research. It is supplied as a light yellow to light brown solid with a reported purity of 97.0%, molecular formula C10H5Na3O10S3, and molecular weight 450.31 g/mol. The compound is typically provided in small, preweighed quantities suitable for laboratory studies.
- Inhibits protein kinase C zeta (PKC-ζ) activity.
- CAS number 31894-34-5.
- Purity 97.0%.
- Molecular formula C10H5Na3O10S3; molecular weight 450.31 g/mol.
- Solid, light yellow to light brown appearance.
- Available in multiple small research quantities (mg scale).
eMolecules Ambeed / Tris(4-aminophenyl)methanol / 1g / 603089382 / A730641 / / 467-62-9 / MFCD00036222 / 305.381 / C19H19N3O
Ambeed / Tris(4-aminophenyl)methanol / 1g / 603089382 / A730641 / / 467-62-9 / MFCD00036222 / 305.381 / C19H19N3O
Apexbio Technology LLC Amfenac Sodium Monohydrate 61618-27-7 10mM (in 1mL DMSO)
Amfenac Sodium Monohydrate (CAS 61618-27-7) is a synthetic non-steroidal anti-inflammatory compound structurally characterized by an acetic acid moiety It functions by inhibiting cyclooxygenase (COX) enzymes consequently suppressing prostaglandin synthesis and mitigating inflammatory processes and pain signaling Amfenac Sodium Monohydrate is utilized in biomedical research to investigate inflammatory pathways and to evaluate non-steroidal analgesic drug effects in cellular and animal models of inflammation Its well-defined inhibitory mechanism makes it a valuable tool for elucidating COX-mediated physiological and pathological responses
Selleck Chemical LLC Sodium citrate dihydrate
Sodium citrate dehydrate (Trisodium citrate dihydrate Citric acid trisodium salt dihydrate) is the preferred anticoagulant
Medchemexpress LLC Dimal-O-CH2COOH | 1620837-47-9 | 96.8% | C13H12N2O7 | 25 MG
diMal-O-CH2COOH is a cleavable ADC linker. It is categorized under Antibody-drug Conjugate/ADC Related and ADC Linker, making it suitable for applications in cancer and cancer targeted therapy.
- Cleavable ADC linker
- White to off-white solid appearance
- Molecular weight: 308.24
- Suitable for antibody-drug conjugate related applications
Medchemexpress LLC MRTX9768 | 2629314-68-5 | 99.48% | 424.43 | 50 MG
MRTX9768 is a potent, selective, orally active, first-in-class PRMT5-MTA complex inhibitor. It inhibits SDMA and cell proliferation in HCT116 MTAP-del cells with marked selectivity over HCT116 MTAP-WT cells. This compound selectively targets MTAP/CDKN2A-deleted tumors, such as glioblastoma, and exhibits a favorable ADME profile.
- Potent and selective PRMT5-MTA complex inhibitor
- Inhibits SDMA and cell proliferation in MTAP-del cells
- Demonstrates dose-dependent inhibition of SDMA in MTAP-del tumors
- Selectively targets MTAP/CDKN2A-deleted tumors, including glioblastoma
- Favorable ADME profile with high bioavailability and moderate to high clearance
Medchemexpress LLC Tos-PEG3-CH2COOH | 1581248-63-6 | C15H22O8S | 10MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker with a tosyl cap and a three-unit polyethylene glycol spacer terminating in a carboxylic acid. It is designed for use in the synthesis of PROTACs and other bifunctional molecules where a short, flexible, polar spacer and a carboxyl functional handle are required.
- Tosyl-capped PEG3 spacer ending in a carboxylic acid for conjugation.
- Provides a short, flexible, hydrophilic linker suitable for cellular applications.
- Terminal carboxyl group enables amide or ester coupling chemistries.
- Compatible with solid-phase and solution-phase synthetic workflows.
- Supplied in research-scale quantities for medicinal chemistry and PROTAC development.
- Molecular formula C15H22O8S, molecular weight ≈362.40 g/mol.
Medchemexpress LLC Iacs-8803 diammonium | 00-00-0 | 98.8% | 726.60 g/mol | C20H29FN12O9P2S2 | 5 MG
IACS-8803 diammonium is a potent cyclic dinucleotide STING agonist for preclinical research that activates the STING pathway and has demonstrated systemic antitumor efficacy. The diammonium salt form improves stability for handling and experimental use and is supplied with supporting analytical and safety documentation for research workflows.
- High purity suitable for research use (98.8%).
- Potent STING agonist activity for immuno-oncology studies.
- Suitable for both in vitro and in vivo preclinical experiments.
- Provided with SDS, COA, HNMR, LCMS, and analytical reports.
- Available in multiple small research pack sizes for dose-ranging studies.
Selleck Chemical LLC Tamoxifen Citrate S1972-250mg
Tamoxifen Citrate is a selective estrogen receptor modulator (SERM) Tamoxifen Citrate is also a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity Tamoxifen induces apoptosis and autophagy
Medchemexpress LLC Fmoc-NH-PEG6-CH2COOH | 437655-96-4 | 99.4% | 5 G
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. This compound leverages the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Cleavable ADC linker
- PEG-based PROTAC linker
- Utilized in antibody-drug conjugate (ADC) synthesis
- Used in PROTAC synthesis
- Leverages intracellular ubiquitin-proteasome system
Medchemexpress LLC IACS-8803 diammonium | 98.8% | 50 MG
IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist known for its robust systemic antitumor efficacy. It has demonstrated superior antitumor activity in in-vivo studies, specifically in mice bearing bilateral B16-OVA melanomas with a 10 μg intra-tumoral injection.
- Highly potent cyclic dinucleotide STING agonist
- Robust systemic antitumor efficacy
- Molecular weight: 726.60
- Molecular formula: C20H29FN12O9P2S2
- Appearance: Solid
- Color: White to off-white
Sigma Aldrich Fine Chemicals Biosciences Trisodium citrate dihydrate meets USP testing specifications | 6132-04-3 | MFCD00150031 | 1KG
Trisodium citrate dihydrate meets USP testing specifications | Purity: 99.0-100.5% anhydrous basis | Mol Wt: 294.1 | 6132-04-3 | MFCD00150031 | 1KG